New Study Links Melatonin to Seasonal Relapse Rates in People with MS

John Guandolo, who authored the book Raising a Jihadi Generation, serves as the founder of the threat management consultancy Along with his professional interests, John Guandolo supports a variety of organizations, such as the National Multiple Sclerosis (MS) Society.

The National MS Society recently released the results of a study on the link between melatonin and relapse rates in MS. In the study, researchers in Boston and Buenos Aires found that melatonin levels were greater in the winter and fall, correlating with decreased relapse rates in individuals with MS. The researchers also found that melatonin, an “internal-clock hormone,” decreased symptoms of a disease similar to MS in mice. The study contradicts previous research that linked lower levels of sunlight-related vitamin D to increased relapse rates.

According to the National MS Society, the research indicates that other factors besides exposure to sunlight could influence the seasonal differences in MS disease occurrence. More research on melatonin is needed, but the research sheds light on the factors that impact MS immune responses—and that information helps drive better treatments.

The study was co-sponsored by the International Progressive MS Alliance, the National MS Society, and other agencies.


Author: John Guandolo

John Guandolo, a counterterrorism consultant at Strategic Engagement Group, Inc., also contributes his time to the Centennial Institute as a Strategic Threats Consultant. The institute, part of Colorado Christian University, works to promote the public understanding of freedom, family, and faith issues. This is accomplished through research, policy analysis, and seminars and conferences with students, staff, faculty, and outside experts such as John Guandolo. He also co-authored Shariah: The Threat To America: An Exercise In Competitive Analysis (Report of Team B II). As Vice President of Strategic Planning and Execution at Strategic Engagement Group, John Guandolo assists law enforcement, government, military, and intelligent community leaders on how to prepare for and respond to terrorist threats. Prior to accepting a position with Strategic Engagement Group, he served the Federal Bureau of Investigation as a Subject Matter Expert. During his time in this role, he developed the agency's first training course on the threat of Muslim extremism and issues posed by the rise of Islamic law. John Guandolo joined the agency as a Special Agent, where he led SWAT team operations, participated in investigations, and served as an Advanced Capability Medic. His accolades include two Awards for Investigative Excellence, given by the U.S. Attorneys’ Offices, and the Defender of the Homeland Award, given by United States Senators John Kyl and Joe Lieberman. John Guandolo graduated from the United States Naval Academy in 1989 and was a Company Commander during his senior year. He is a member of the Force Recon Association, a non-profit fraternal organization that promotes the fellowship of those who have served in military reconnaissance units. John Guandolo also holds membership in the Knights of Columbus, the Veterans of Foreign Wars, The American Legion, and the Sovereign Military Order of Malta, and the Order of St. Crispin. He enjoys hiking, competing in triathlons, and camping.

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